SDer wrote:
> HaltingState <HaltingState@[EMAIL PROTECTED]
> wrote in
> news:gf32qj$nre$1@[EMAIL PROTECTED]
>
>> SDer wrote:
>>> HaltingState <HaltingState@[EMAIL PROTECTED]
> wrote in
>>> news:gf0t41$l28$1@[EMAIL PROTECTED]
>>>
>>>> Post any studies on creatine that you may have come across.
>>>>
>>>>
>>>> While the role of creatine in preventing muscle (peripheral) fatigue
>>>> for high performance athletes is well understood, its biochemical
>>>> role in prevention of mental (central) fatigue is not. Creatine is
>>>> abundant in muscles and the brain and after phosphorylation used as
>>>> an energy source for adenosine triphosphate synthesis. Using
>>>> double-blind placebo-controlled paradigm, we demonstrated that
>>>> dietary supplement of creatine (8 g/day for 5 days) reduces mental
>>>> fatigue when subjects repeatedly perform a simple mathematical
>>>> calculation. After taking the creatine supplement, task-evoked
>>>> increase of cerebral oxygenated hemoglobin in the brains of subjects
>>>> measured by near infrared spectroscopy was significantly reduced,
>>>> which is compatible with increased oxygen utilization in the brain.
>>>>
>>>> http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0H-454TR7
>>>> 3-
>>>> 2&_user=681891&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C00003
>>>> 74
>>>> 19&_version=1&_urlVersion=0&_userid=681891&md5=8cb5a175782e7cdd9dadb3
>>>> b7 c8d165db
>>>>
>>> I have found that creatine can help with mental fatigue, but the
>>> problem I faced was that it was hard on the stomach, no matter what
>>> brand I tried. Its EEC form was also great.
>> EEC form? What is EEC?
>
> Ethyl-Ester-Creatine, which is better in pill form as it tastes like
> battery acid.
>
>> It is much easier to take down if you use green tea to dissolve it. I
>> found that for whatever reason that it dissolves more effectively and
>> gives less stomach irritation. Some drinks do not seem to dissolve it
>> at all.
>
> I hadn't thought of that.
>
>> I am currently looking at arginine, glycine, and methionine
>> supplementation as a means of increasing creatine concentration beyond
>> what would normally be possible via dietary intake of creatine alone.
>>
>> Glycine also seems to have other interesting nootropic effects, but I
>> have no tried it yet personally.
>>
>
> I would be sceptical about arginine and methionine. Arginine can mess up
> your blood pressure, which might be a good or even pleasant thing
> sometimes, depending on your situation. Methionine can make you really
> sick if your methylic cycle is already messed (again depending on your
> individual situation, but a word of caution is never a bad idea).
Do you have any information on Methionine inducing disease? That is
interesting and I have not heard about that before.
I was told that chronic arginine administration upregulates enzymes that
metabolize NO and possible down regulates enzymes that convery argininte
into NO. Thereby reducing the basal level of NO and hence reducing
vaso-dilation and blood flow when arginine is not being used. I however
have not read anything specific on this. Any information or experience
that you could share would be appreciated.
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