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Re: Effects of creatine on mental fatigue and cerebral hemoglobin

by HaltingState <HaltingState@[EMAIL PROTECTED] > Nov 8, 2008 at 10:11 PM

SDer wrote:
> HaltingState <HaltingState@[EMAIL PROTECTED]
> wrote in
> news:gf32qj$nre$1@[EMAIL PROTECTED]
 
> 
>> SDer wrote:
>>> HaltingState <HaltingState@[EMAIL PROTECTED]
> wrote in
>>> news:gf0t41$l28$1@[EMAIL PROTECTED]
 
>>>
>>>> Post any studies on creatine that you may have come across.
>>>>
>>>>
>>>> While the role of creatine in preventing muscle (peripheral) fatigue
>>>> for high performance athletes is well understood, its biochemical
>>>> role in prevention of mental (central) fatigue is not. Creatine is
>>>> abundant in muscles and the brain and after phosphorylation used as
>>>> an energy source for adenosine triphosphate synthesis. Using
>>>> double-blind placebo-controlled paradigm, we demonstrated that
>>>> dietary supplement of creatine (8 g/day for 5 days) reduces mental
>>>> fatigue when subjects repeatedly perform a simple mathematical
>>>> calculation. After taking the creatine supplement, task-evoked
>>>> increase of cerebral oxygenated hemoglobin in the brains of subjects
>>>> measured by near infrared spectroscopy was significantly reduced,
>>>> which is compatible with increased oxygen utilization in the brain.
>>>>
>>>> http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0H-454TR7
>>>> 3- 
>>>> 2&_user=681891&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C00003
>>>> 74 
>>>> 19&_version=1&_urlVersion=0&_userid=681891&md5=8cb5a175782e7cdd9dadb3
>>>> b7 c8d165db 
>>>>
>>> I have found that creatine can help with mental fatigue, but the
>>> problem I faced was that it was hard on the stomach, no matter what
>>> brand I tried. Its EEC form was also great.
>> EEC form?  What is EEC?
> 
> Ethyl-Ester-Creatine, which is better in pill form as it tastes like 
> battery acid.
> 
>> It is much easier to take down if you use green tea to dissolve it.  I
>> found that for whatever reason that it dissolves more effectively and 
>> gives less stomach irritation. Some drinks do not seem to dissolve it
>> at all.
> 
> I hadn't thought of that.
> 
>> I am currently looking at arginine, glycine, and methionine 
>> supplementation as a means of increasing creatine concentration beyond
>> what would normally be possible via dietary intake of creatine alone.
>>
>> Glycine also seems to have other interesting nootropic effects, but I 
>> have no tried it yet personally.
>>
> 
> I would be sceptical about arginine and methionine. Arginine can mess up

> your blood pressure, which might be a good or even pleasant thing 
> sometimes, depending on your situation. Methionine can make you really 
> sick if your methylic cycle is already messed (again depending on your 
> individual situation, but a word of caution is never a bad idea).

I doubt I would supplement more than a gram a day of each of those. 
Most likely more than 500mg of each twice a day would not have any 
additional effect on creatine synthesis.
 




 7 Posts in Topic:
Effects of creatine on mental fatigue and cerebral hemoglobin ox
HaltingState <HaltingS  2008-11-07 03:11:02 
Re: Effects of creatine on mental fatigue and cerebral hemoglobi
SDer <sder@[EMAIL PROT  2008-11-08 02:42:33 
Re: Effects of creatine on mental fatigue and cerebral hemoglobi
HaltingState <HaltingS  2008-11-07 23:00:39 
Re: Effects of creatine on mental fatigue and cerebral hemoglobi
SDer <sder@[EMAIL PROT  2008-11-08 22:19:48 
Re: Effects of creatine on mental fatigue and cerebral hemoglobi
HaltingState <HaltingS  2008-11-08 22:11:31 
Re: Effects of creatine on mental fatigue and cerebral hemoglobi
HaltingState <HaltingS  2008-11-09 00:56:31 
Re: Effects of creatine on mental fatigue and cerebral hemoglobi
SDer <sder@[EMAIL PROT  2008-11-10 03:00:15 

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